Inhibiting vascular endothelial growth factor receptor-2 signaling reduces tumor burden in the ApcMin/+ mouse model of early intestinal cancer.

Goodlad, R A

Inhibiting vascular endothelial growth factor receptor-2 signaling reduces tumor burden in the ApcMin/+ mouse model of early intestinal cancer. [electronic resource] - Carcinogenesis Oct 2006 - 2133-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0143-3334

10.1093/carcin/bgl113 doi


Adenoma--prevention & control
Animals
Female
Genes, APC--physiology
Intestinal Neoplasms--prevention & control
Intestinal Polyps--drug therapy
Male
Mice
Mice, Inbred C57BL
Quinazolines--therapeutic use
RNA, Messenger--analysis
Signal Transduction--drug effects
Splenomegaly--prevention & control
Vascular Endothelial Growth Factor Receptor-2--antagonists & inhibitors