Cytokine blockade inhibits hepatic tissue inhibitor of metalloproteinase-1 expression and up-regulates matrix metalloproteinase-9 in toxic liver injury.

Roderfeld, Martin

Cytokine blockade inhibits hepatic tissue inhibitor of metalloproteinase-1 expression and up-regulates matrix metalloproteinase-9 in toxic liver injury. [electronic resource] - Liver international : official journal of the International Association for the Study of the Liver Jun 2006 - 579-86 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1478-3223

10.1111/j.1478-3231.2006.01271.x doi


Animals
Carbon Tetrachloride
Cytokines--administration & dosage
Disease Models, Animal
Etanercept
Immunoglobulin G--administration & dosage
Interleukin 1 Receptor Antagonist Protein--administration & dosage
Interleukin-1beta--antagonists & inhibitors
Liver--metabolism
Liver Cirrhosis--chemically induced
Male
Matrix Metalloproteinase 9--biosynthesis
Mice
Mice, Inbred C57BL
Rats
Rats, Sprague-Dawley
Receptors, Tumor Necrosis Factor--administration & dosage
Tissue Inhibitor of Metalloproteinase-1--antagonists & inhibitors
Tumor Necrosis Factor-alpha--antagonists & inhibitors
Up-Regulation--drug effects