Lack of cyclic AMP-specific phosphodiesterase 4 activation during naloxone-precipitated morphine withdrawal in rats.

Kimura, Megumi

Lack of cyclic AMP-specific phosphodiesterase 4 activation during naloxone-precipitated morphine withdrawal in rats. [electronic resource] - Neuroscience letters Aug 2006 - 107-11 p. digital

Publication Type: Journal Article

0304-3940

10.1016/j.neulet.2006.05.014 doi


3',5'-Cyclic-AMP Phosphodiesterases--metabolism
Animals
Brain--drug effects
Cyclic AMP--metabolism
Cyclic Nucleotide Phosphodiesterases, Type 4
Enzyme Activation
Male
Morphine--administration & dosage
Naloxone--pharmacology
Rats
Rats, Sprague-Dawley
Rolipram--pharmacokinetics
Substance Withdrawal Syndrome--enzymology