Hyperactivation of mammalian target of rapamycin (mTOR) signaling by a gain-of-function mutant of the Rheb GTPase.

Yan, Lijun

Hyperactivation of mammalian target of rapamycin (mTOR) signaling by a gain-of-function mutant of the Rheb GTPase. [electronic resource] - The Journal of biological chemistry Jul 2006 - 19793-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.C600028200 doi


Amino Acid Sequence
Animals
Cell Line
Conserved Sequence
Enzyme Activation
GTP Phosphohydrolases--metabolism
Guanosine Triphosphate--metabolism
Humans
Kidney
Molecular Sequence Data
Monomeric GTP-Binding Proteins--chemistry
Mutation
Neuropeptides--chemistry
Phosphatidylinositol 3-Kinases--metabolism
Protein Kinases--metabolism
Ras Homolog Enriched in Brain Protein
Sequence Alignment
Sequence Homology, Amino Acid
Signal Transduction
TOR Serine-Threonine Kinases
rho GTP-Binding Proteins--genetics