KRAS(D13) Promotes apoptosis of human colorectal tumor cells by ReovirusT3D and oxaliplatin but not by tumor necrosis factor-related apoptosis-inducing ligand.

Smakman, Niels

KRAS(D13) Promotes apoptosis of human colorectal tumor cells by ReovirusT3D and oxaliplatin but not by tumor necrosis factor-related apoptosis-inducing ligand. [electronic resource] - Cancer research May 2006 - 5403-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0008-5472

10.1158/0008-5472.CAN-05-4108 doi


Apoptosis--drug effects
Apoptosis Regulatory Proteins--pharmacology
Colorectal Neoplasms--drug therapy
Combined Modality Therapy
Gene Deletion
HCT116 Cells
HT29 Cells
Humans
Membrane Glycoproteins--pharmacology
Mutation
Oncolytic Virotherapy--methods
Organoplatinum Compounds--pharmacology
Oxaliplatin
Retroviridae--genetics
TNF-Related Apoptosis-Inducing Ligand
Tumor Necrosis Factor-alpha--pharmacology
Tumor Suppressor Protein p53--genetics
Virus Replication
beta Catenin--genetics
ras Proteins--deficiency