Potentiation of the anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the kinase inhibitor Staurosporine or its clinically relevant analogue UCN-01.
Yeow, W-S
Potentiation of the anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the kinase inhibitor Staurosporine or its clinically relevant analogue UCN-01. [electronic resource] - British journal of cancer May 2006 - 1436-45 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Intramural
0007-0920
10.1038/sj.bjc.6603132 doi
Anticonvulsants--pharmacology
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Dose-Response Relationship, Drug
Drug Synergism
Enzyme Inhibitors--pharmacology
Histone Deacetylase Inhibitors
Humans
NF-kappa B--genetics
Neoplasms--drug therapy
Staurosporine--analogs & derivatives
Tumor Cells, Cultured
Valproic Acid--pharmacology
Potentiation of the anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the kinase inhibitor Staurosporine or its clinically relevant analogue UCN-01. [electronic resource] - British journal of cancer May 2006 - 1436-45 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Intramural
0007-0920
10.1038/sj.bjc.6603132 doi
Anticonvulsants--pharmacology
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Dose-Response Relationship, Drug
Drug Synergism
Enzyme Inhibitors--pharmacology
Histone Deacetylase Inhibitors
Humans
NF-kappa B--genetics
Neoplasms--drug therapy
Staurosporine--analogs & derivatives
Tumor Cells, Cultured
Valproic Acid--pharmacology