Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors.

Mitra, S K

Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors. [electronic resource] - Oncogene Sep 2006 - 5969-84 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0950-9232

10.1038/sj.onc.1209588 doi


Animals
Breast Neoplasms--blood supply
Carcinoma--blood supply
Cell Line, Transformed
Cell Line, Tumor
Cells, Cultured
Clone Cells
Female
Focal Adhesion Protein-Tyrosine Kinases--deficiency
Humans
Mammary Neoplasms, Animal--blood supply
Mice
Mice, Inbred BALB C
Mice, Nude
Neovascularization, Pathologic--enzymology
Phosphorylation
Protein-Tyrosine Kinases--physiology
Signal Transduction--genetics
Tyrosine--metabolism