Mechanism-based cofactor derivatization of a copper amine oxidase by a branched primary amine recruits the oxidase activity of the enzyme to turn inactivator into substrate.

Qiao, Chunhua

Mechanism-based cofactor derivatization of a copper amine oxidase by a branched primary amine recruits the oxidase activity of the enzyme to turn inactivator into substrate. [electronic resource] - Journal of the American Chemical Society May 2006 - 6206-19 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

0002-7863

10.1021/ja058838f doi


Amine Oxidase (Copper-Containing)--antagonists & inhibitors
Amines--chemistry
Animals
Binding Sites
Cattle
Kinetics
Magnetic Resonance Spectroscopy
Mass Spectrometry
Models, Chemical
Quinones--chemistry
Spectrophotometry, Ultraviolet
Thiophenes--chemistry