Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation.

Ferby, Ingvar

Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation. [electronic resource] - Nature medicine May 2006 - 568-73 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1078-8956

10.1038/nm1401 doi


Adaptor Proteins, Signal Transducing--genetics
Animals
Cell Proliferation
ErbB Receptors--metabolism
Gefitinib
Humans
Intracellular Signaling Peptides and Proteins
Keratinocytes--cytology
MAP Kinase Signaling System--physiology
Mice
Mice, Inbred C57BL
Mice, Knockout
Mitogen-Activated Protein Kinases--metabolism
Morphogenesis
Neoplasms--metabolism
Protein Kinase Inhibitors--metabolism
Quinazolines--metabolism
Skin--cytology