Assessing the acid-base and conformational properties of histidine residues in human prion protein (125-228) by means of pK(a) calculations and molecular dynamics simulations.

Langella, Emma

Assessing the acid-base and conformational properties of histidine residues in human prion protein (125-228) by means of pK(a) calculations and molecular dynamics simulations. [electronic resource] - Proteins Jul 2006 - 167-77 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1097-0134

10.1002/prot.20979 doi


Amino Acid Sequence
Computer Simulation
Histidine
Humans
Hydrogen-Ion Concentration
Kinetics
Magnetic Resonance Spectroscopy
Models, Molecular
Peptide Fragments--chemistry
Prions--chemistry
Protein Conformation