Two-hit model for progression of medulloblastoma preneoplasia in Patched heterozygous mice.

Pazzaglia, S

Two-hit model for progression of medulloblastoma preneoplasia in Patched heterozygous mice. [electronic resource] - Oncogene Sep 2006 - 5575-80 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0950-9232

10.1038/sj.onc.1209544 doi


Aging
Animals
Cerebellar Neoplasms--genetics
Chromosomes, Mammalian
Disease Models, Animal
Disease Progression
Hedgehog Proteins
Loss of Heterozygosity
Medulloblastoma--genetics
Mice
Mice, Inbred C57BL
Patched Receptors
Patched-1 Receptor
Precancerous Conditions--genetics
Radiation, Ionizing
Receptors, Cell Surface--genetics
Signal Transduction
Trans-Activators--metabolism