Insulin-like growth factor-1 and PTEN deletion enhance cardiac L-type Ca2+ currents via increased PI3Kalpha/PKB signaling.

Sun, Hui

Insulin-like growth factor-1 and PTEN deletion enhance cardiac L-type Ca2+ currents via increased PI3Kalpha/PKB signaling. [electronic resource] - Circulation research Jun 2006 - 1390-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1524-4571

10.1161/01.RES.0000223321.34482.8c doi


Animals
Calcium Channels, L-Type--physiology
Class I Phosphatidylinositol 3-Kinases
Electric Conductivity
Gene Deletion
Genes, Dominant
Insulin-Like Growth Factor I--deficiency
Mice
Mice, Knockout
Mice, Transgenic
Myocardium--metabolism
PTEN Phosphohydrolase--deficiency
Phosphatidylinositol 3-Kinases--genetics
Proto-Oncogene Proteins c-akt--genetics
Signal Transduction