Carboxylate bioisosteres of pregabalin.

Schwarz, Jacob B

Carboxylate bioisosteres of pregabalin. [electronic resource] - Bioorganic & medicinal chemistry letters Jul 2006 - 3559-63 p. digital

Publication Type: Journal Article

0960-894X

10.1016/j.bmcl.2006.03.083 doi


Amines--chemical synthesis
Animals
Anticonvulsants--chemical synthesis
Binding Sites
Carboxylic Acids--chemistry
Cyclohexanecarboxylic Acids--chemical synthesis
Disease Models, Animal
Drug Evaluation, Preclinical
Epilepsy, Reflex--prevention & control
Gabapentin
Mice
Mice, Inbred DBA
Molecular Structure
Pregabalin
Protein Subunits--drug effects
Stereoisomerism
Structure-Activity Relationship
gamma-Aminobutyric Acid--analogs & derivatives