N6-(3-iodobenzyl)-adenosine-5'-N-methylcarboxamide confers cardioprotection at reperfusion by inhibiting mitochondrial permeability transition pore opening via glycogen synthase kinase 3 beta.

Park, Sung-Sik

N6-(3-iodobenzyl)-adenosine-5'-N-methylcarboxamide confers cardioprotection at reperfusion by inhibiting mitochondrial permeability transition pore opening via glycogen synthase kinase 3 beta. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jul 2006 - 124-31 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0022-3565

10.1124/jpet.106.101477 doi


Adenosine--analogs & derivatives
Animals
Cardiotonic Agents--pharmacology
Glycogen Synthase Kinase 3--antagonists & inhibitors
Glycogen Synthase Kinase 3 beta
Male
Mitochondrial Membrane Transport Proteins--antagonists & inhibitors
Mitochondrial Permeability Transition Pore
Myocardial Reperfusion Injury--enzymology
Rats
Rats, Wistar