Significant inhibition of TRAIL-mediated fibroblast-like synovial cell apoptosis by IFN-gamma through JAK/STAT pathway by translational regulation.

Tamai, Mami

Significant inhibition of TRAIL-mediated fibroblast-like synovial cell apoptosis by IFN-gamma through JAK/STAT pathway by translational regulation. [electronic resource] - The Journal of laboratory and clinical medicine Apr 2006 - 182-90 p. digital

Publication Type: Journal Article

0022-2143

10.1016/j.lab.2005.12.001 doi


Apoptosis--drug effects
Apoptosis Regulatory Proteins--metabolism
Fibroblasts--cytology
Humans
In Vitro Techniques
Interferon-gamma--pharmacology
MAP Kinase Signaling System--drug effects
Membrane Glycoproteins--metabolism
Phosphorylation
Protein Biosynthesis
Protein-Tyrosine Kinases--metabolism
Recombinant Proteins
STAT Transcription Factors--metabolism
STAT1 Transcription Factor
Signal Transduction--drug effects
Synovial Membrane--cytology
TNF-Related Apoptosis-Inducing Ligand
Tumor Necrosis Factor-alpha--metabolism