The role of tyrosine 177 in human 11beta-hydroxysteroid dehydrogenase type 1 in substrate and inhibitor binding: an unlikely hydrogen bond donor for the substrate.
Kim, Ki Won
The role of tyrosine 177 in human 11beta-hydroxysteroid dehydrogenase type 1 in substrate and inhibitor binding: an unlikely hydrogen bond donor for the substrate. [electronic resource] - Biochimica et biophysica acta Apr 2006 - 824-30 p. digital
Publication Type: Journal Article
0006-3002
10.1016/j.bbapap.2006.02.008 doi
11-beta-Hydroxysteroid Dehydrogenase Type 1--antagonists & inhibitors
Amino Acid Sequence
Amino Acid Substitution
Animals
Binding Sites
CHO Cells
Carbenoxolone--pharmacology
Cortisone--metabolism
Cricetinae
Cricetulus
Glycyrrhetinic Acid--pharmacology
Humans
Hydrocortisone--metabolism
Hydrogen Bonding
Kinetics
Models, Molecular
Substrate Specificity
Tyrosine--chemistry
The role of tyrosine 177 in human 11beta-hydroxysteroid dehydrogenase type 1 in substrate and inhibitor binding: an unlikely hydrogen bond donor for the substrate. [electronic resource] - Biochimica et biophysica acta Apr 2006 - 824-30 p. digital
Publication Type: Journal Article
0006-3002
10.1016/j.bbapap.2006.02.008 doi
11-beta-Hydroxysteroid Dehydrogenase Type 1--antagonists & inhibitors
Amino Acid Sequence
Amino Acid Substitution
Animals
Binding Sites
CHO Cells
Carbenoxolone--pharmacology
Cortisone--metabolism
Cricetinae
Cricetulus
Glycyrrhetinic Acid--pharmacology
Humans
Hydrocortisone--metabolism
Hydrogen Bonding
Kinetics
Models, Molecular
Substrate Specificity
Tyrosine--chemistry