p16 inhibits matrix metalloproteinase-2 expression via suppression of Sp1-mediated gene transcription.

Wang, Chie-Hong

p16 inhibits matrix metalloproteinase-2 expression via suppression of Sp1-mediated gene transcription. [electronic resource] - Journal of cellular physiology Jul 2006 - 246-52 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9541

10.1002/jcp.20660 doi


Cyclin A--analysis
Cyclin-Dependent Kinase Inhibitor p16--pharmacology
Down-Regulation--physiology
Gene Expression Regulation, Enzymologic--drug effects
Gene Expression Regulation, Neoplastic--physiology
Humans
Immunoblotting
Immunoprecipitation
Lung Neoplasms--chemistry
Matrix Metalloproteinase 2--analysis
Neoplasm Invasiveness--physiopathology
Neoplasm Metastasis--physiopathology
Neovascularization, Pathologic--genetics
Oligonucleotide Array Sequence Analysis
Promoter Regions, Genetic--drug effects
Protein Binding--drug effects
Reverse Transcriptase Polymerase Chain Reaction
Sp1 Transcription Factor--analysis
Transcription, Genetic--drug effects
Tumor Cells, Cultured