Mitochondrial thioredoxin-2 has a key role in determining tumor necrosis factor-alpha-induced reactive oxygen species generation, NF-kappaB activation, and apoptosis.

Hansen, Jason M

Mitochondrial thioredoxin-2 has a key role in determining tumor necrosis factor-alpha-induced reactive oxygen species generation, NF-kappaB activation, and apoptosis. [electronic resource] - Toxicological sciences : an official journal of the Society of Toxicology Jun 2006 - 643-50 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1096-6080

10.1093/toxsci/kfj175 doi


Apoptosis
HeLa Cells
Humans
Mitochondria--drug effects
Mitochondrial Proteins--metabolism
NF-kappa B--metabolism
Reactive Oxygen Species--metabolism
Thioredoxins--metabolism
Tumor Necrosis Factor-alpha--pharmacology