Up-regulated expression of the CXCR2 ligand KC/GRO-alpha in atherosclerotic lesions plays a central role in macrophage accumulation and lesion progression.

Boisvert, William A

Up-regulated expression of the CXCR2 ligand KC/GRO-alpha in atherosclerotic lesions plays a central role in macrophage accumulation and lesion progression. [electronic resource] - The American journal of pathology Apr 2006 - 1385-95 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

0002-9440

10.2353/ajpath.2006.040748 doi


Animals
Aorta--metabolism
Atherosclerosis--metabolism
Chemokine CCL2--metabolism
Chemokine CXCL1
Chemokines, CXC--biosynthesis
Chimera
Intercellular Signaling Peptides and Proteins--biosynthesis
Leukocytes--metabolism
Macrophages--metabolism
Male
Mice
Mice, Knockout
Receptors, Interleukin-8B--biosynthesis
Up-Regulation