Involvement of the TTX-resistant sodium channel Nav 1.8 in inflammatory and neuropathic, but not post-operative, pain states.

Joshi, S K

Involvement of the TTX-resistant sodium channel Nav 1.8 in inflammatory and neuropathic, but not post-operative, pain states. [electronic resource] - Pain Jul 2006 - 75-82 p. digital

Publication Type: Comparative Study; Journal Article

1872-6623

10.1016/j.pain.2006.02.011 doi


Animals
Behavior, Animal
Drug Evaluation, Preclinical
Freund's Adjuvant--toxicity
Hyperalgesia--drug therapy
Inflammation--physiopathology
Injections, Spinal
Ion Transport
Ligation
Male
NAV1.8 Voltage-Gated Sodium Channel
Nerve Tissue Proteins--antagonists & inhibitors
Neuralgia--chemically induced
Neurons, Afferent--drug effects
Oligodeoxyribonucleotides, Antisense--pharmacology
Pain, Postoperative--physiopathology
Patch-Clamp Techniques
Pressure--adverse effects
Rats
Rats, Sprague-Dawley
Sciatic Nerve--injuries
Sodium--physiology
Sodium Channels--drug effects
Spinal Nerves--injuries
Stress, Mechanical
Tetrodotoxin--pharmacology
Vincristine--toxicity