Phosphate alkylation in different DNA substrates: the role of local DNA sequence and electrophile character in determining the nonrandom nature of phosphotriester adduct formation.

Le Pla, Rachel C

Phosphate alkylation in different DNA substrates: the role of local DNA sequence and electrophile character in determining the nonrandom nature of phosphotriester adduct formation. [electronic resource] - Chemical research in toxicology Mar 2006 - 407-13 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0893-228X

10.1021/tx050298c doi


Alkylating Agents--chemistry
Alkylation
Autoradiography
Buffers
Cell Line
Culture Media
DNA--drug effects
Electrophoresis, Polyacrylamide Gel
Ethylnitrosourea--pharmacology
Humans
Methylnitrosourea--pharmacology
Oligonucleotides--chemistry
Oxygen--chemistry
Phosphates--metabolism
Sulfuric Acid Esters--pharmacology