First evaluation of the potential effectiveness in muscular dystrophy of a novel chimeric compound, BN 82270, acting as calpain-inhibitor and anti-oxidant.
Burdi, Rosa
First evaluation of the potential effectiveness in muscular dystrophy of a novel chimeric compound, BN 82270, acting as calpain-inhibitor and anti-oxidant. [electronic resource] - Neuromuscular disorders : NMD Apr 2006 - 237-48 p. digital
Publication Type: Journal Article
0960-8966
10.1016/j.nmd.2006.01.013 doi
Animals
Antioxidants--pharmacology
Biomechanical Phenomena
Body Weight
Calpain--physiology
Chloride Channels--drug effects
Creatine Kinase--blood
Diaphragm--drug effects
Glycoproteins--pharmacology
Hindlimb
Male
Mice
Mice, Inbred C57BL
Mice, Inbred mdx
Muscle Fibers, Skeletal--drug effects
Muscle, Skeletal--drug effects
Muscular Dystrophy, Animal--drug therapy
Phenothiazines--therapeutic use
Physical Conditioning, Animal
Prodrugs--pharmacology
Rats
Rats, Sprague-Dawley
Transforming Growth Factor beta--blood
Transforming Growth Factor beta1
First evaluation of the potential effectiveness in muscular dystrophy of a novel chimeric compound, BN 82270, acting as calpain-inhibitor and anti-oxidant. [electronic resource] - Neuromuscular disorders : NMD Apr 2006 - 237-48 p. digital
Publication Type: Journal Article
0960-8966
10.1016/j.nmd.2006.01.013 doi
Animals
Antioxidants--pharmacology
Biomechanical Phenomena
Body Weight
Calpain--physiology
Chloride Channels--drug effects
Creatine Kinase--blood
Diaphragm--drug effects
Glycoproteins--pharmacology
Hindlimb
Male
Mice
Mice, Inbred C57BL
Mice, Inbred mdx
Muscle Fibers, Skeletal--drug effects
Muscle, Skeletal--drug effects
Muscular Dystrophy, Animal--drug therapy
Phenothiazines--therapeutic use
Physical Conditioning, Animal
Prodrugs--pharmacology
Rats
Rats, Sprague-Dawley
Transforming Growth Factor beta--blood
Transforming Growth Factor beta1