Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling.

Lengner, Christopher J

Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling. [electronic resource] - The Journal of cell biology Mar 2006 - 909-21 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

0021-9525

10.1083/jcb.200508130 doi


Animals
Bone Development--genetics
Bone Neoplasms--genetics
Cell Differentiation--genetics
Cell Proliferation
Cell Transformation, Neoplastic--genetics
Cells, Cultured
Core Binding Factor Alpha 1 Subunit--metabolism
Gene Expression Regulation, Developmental--genetics
Genetic Predisposition to Disease--genetics
Mice
Mice, Transgenic
Osteoblasts--cytology
Osteosarcoma--genetics
Proto-Oncogene Proteins c-mdm2--genetics
Signal Transduction--genetics
Skeleton
Stem Cells--cytology
Tumor Suppressor Protein p53--genetics
Up-Regulation--physiology