Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis.
Malhi, Harmeet
Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis. [electronic resource] - The Journal of biological chemistry Apr 2006 - 12093-101 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M510660200 doi
Animals
Apoptosis--physiology
Apoptosis Regulatory Proteins--antagonists & inhibitors
Bcl-2-Like Protein 11
Carcinoma, Hepatocellular--metabolism
Cathepsin B--genetics
Cytochromes c--metabolism
Fatty Acids, Nonesterified--pharmacology
Fatty Liver
Flow Cytometry
Hepatocytes--cytology
JNK Mitogen-Activated Protein Kinases--genetics
Liver Neoplasms--metabolism
Membrane Proteins--antagonists & inhibitors
Mice
Mice, Inbred C57BL
Mice, Knockout
Mitochondria--metabolism
Proto-Oncogene Proteins--antagonists & inhibitors
RNA, Small Interfering--pharmacology
Rats
Signal Transduction
bcl-2-Associated X Protein--metabolism
Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis. [electronic resource] - The Journal of biological chemistry Apr 2006 - 12093-101 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M510660200 doi
Animals
Apoptosis--physiology
Apoptosis Regulatory Proteins--antagonists & inhibitors
Bcl-2-Like Protein 11
Carcinoma, Hepatocellular--metabolism
Cathepsin B--genetics
Cytochromes c--metabolism
Fatty Acids, Nonesterified--pharmacology
Fatty Liver
Flow Cytometry
Hepatocytes--cytology
JNK Mitogen-Activated Protein Kinases--genetics
Liver Neoplasms--metabolism
Membrane Proteins--antagonists & inhibitors
Mice
Mice, Inbred C57BL
Mice, Knockout
Mitochondria--metabolism
Proto-Oncogene Proteins--antagonists & inhibitors
RNA, Small Interfering--pharmacology
Rats
Signal Transduction
bcl-2-Associated X Protein--metabolism