Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia.

Walter, Joy T

Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia. [electronic resource] - Nature neuroscience Mar 2006 - 389-97 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1097-6256

10.1038/nn1648 doi


Action Potentials--drug effects
Animals
Benzimidazoles--pharmacology
Biological Clocks--drug effects
Calcium Channel Agonists--pharmacology
Calcium Channel Blockers--pharmacology
Calcium Channels, P-Type--drug effects
Cerebellar Ataxia--genetics
Cerebellar Cortex--drug effects
Down-Regulation--genetics
Female
Male
Mice
Mice, Neurologic Mutants
Mice, Transgenic
Potassium Channels, Calcium-Activated--genetics
Purkinje Cells--drug effects
Synaptic Membranes--genetics
Synaptic Transmission--drug effects