Block of T cell development in P53-deficient mice accelerates development of lymphomas with characteristic RAG-dependent cytogenetic alterations.

Haines, Brian B

Block of T cell development in P53-deficient mice accelerates development of lymphomas with characteristic RAG-dependent cytogenetic alterations. [electronic resource] - Cancer cell Feb 2006 - 109-20 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1535-6108

10.1016/j.ccr.2006.01.004 doi


Animals
Apoptosis
Cell Line, Tumor
Chromosome Aberrations
DNA Damage
DNA-Binding Proteins--genetics
Gene Rearrangement, T-Lymphocyte--genetics
Genes, T-Cell Receptor beta--genetics
Lymphoma--genetics
Mice
Mice, Knockout
Sequence Deletion--genetics
Spectral Karyotyping
T-Lymphocytes--cytology
Thymus Gland--cytology
Tumor Suppressor Protein p53--deficiency