Elastin fragments drive disease progression in a murine model of emphysema.

Houghton, A McGarry

Elastin fragments drive disease progression in a murine model of emphysema. [electronic resource] - The Journal of clinical investigation Mar 2006 - 753-9 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0021-9738

10.1172/JCI25617 doi


Animals
Bronchoalveolar Lavage Fluid
Chemotaxis, Leukocyte
Disease Models, Animal
Disease Progression
Elastin--physiology
Emphysema--metabolism
Macrophages, Alveolar--metabolism
Matrix Metalloproteinase 12
Metalloendopeptidases--deficiency
Mice
Mice, Inbred C57BL
Mice, Knockout
Monocytes--metabolism
Peptide Fragments--physiology
Pulmonary Alveoli--metabolism
Smoking