Conversion of 5-iodo-2-pyrimidinone-2'-deoxyribose to 5-iodo-deoxyuridine by aldehyde oxidase. Implication in hepatotropic drug design.

Chang, C N

Conversion of 5-iodo-2-pyrimidinone-2'-deoxyribose to 5-iodo-deoxyuridine by aldehyde oxidase. Implication in hepatotropic drug design. [electronic resource] - Biochemical pharmacology May 1992 - 2269-73 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0006-2952

10.1016/0006-2952(92)90186-m doi


Aldehyde Oxidase
Aldehyde Oxidoreductases--metabolism
Animals
Drug Design
Humans
Idoxuridine--metabolism
Kidney--enzymology
Pyrimidine Nucleosides--metabolism
Radiation-Sensitizing Agents--metabolism
Rats
Spleen--enzymology
Substrate Specificity
Tissue Extracts--metabolism