Peroxynitrite-modified collagen-II induces p38/ERK and NF-kappaB-dependent synthesis of prostaglandin E2 and nitric oxide in chondrogenically differentiated mesenchymal progenitor cells.

Whiteman, M

Peroxynitrite-modified collagen-II induces p38/ERK and NF-kappaB-dependent synthesis of prostaglandin E2 and nitric oxide in chondrogenically differentiated mesenchymal progenitor cells. [electronic resource] - Osteoarthritis and cartilage May 2006 - 460-70 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1063-4584

10.1016/j.joca.2005.11.002 doi


Arthritis--physiopathology
Cell Differentiation--physiology
Cells, Cultured
Collagen Type II--metabolism
Cyclooxygenase 2--metabolism
Dinoprostone--biosynthesis
Enzyme Activation
Extracellular Signal-Regulated MAP Kinases--metabolism
Humans
Membrane Proteins--metabolism
Mesenchymal Stem Cells--metabolism
Mitogen-Activated Protein Kinases--metabolism
NF-kappa B--metabolism
Nitric Oxide--biosynthesis
Nitric Oxide Synthase Type II--metabolism
Peroxynitrous Acid--metabolism
Phosphorylation
p38 Mitogen-Activated Protein Kinases--metabolism