Sichuan pepper extracts block the PAK1/cyclin D1 pathway and the growth of NF1-deficient cancer xenograft in mice.
Hirokawa, Yumiko
Sichuan pepper extracts block the PAK1/cyclin D1 pathway and the growth of NF1-deficient cancer xenograft in mice. [electronic resource] - Cancer biology & therapy Mar 2006 - 305-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1538-4047
10.4161/cbt.5.3.2404 doi
Animals
Antimitotic Agents--pharmacology
Cell Line, Tumor
Cell Proliferation--drug effects
Cyclin D1--metabolism
Down-Regulation
Enzyme Inhibitors--pharmacology
Female
Humans
Mice
Mice, Inbred BALB C
Neoplasm Transplantation
Nerve Sheath Neoplasms--pathology
Neurofibromatosis 1--drug therapy
Neurofibromin 1--genetics
Phytotherapy
Plant Extracts--pharmacology
Protein Serine-Threonine Kinases--antagonists & inhibitors
Signal Transduction
Transplantation, Heterologous
Zanthoxylum--chemistry
p21-Activated Kinases
Sichuan pepper extracts block the PAK1/cyclin D1 pathway and the growth of NF1-deficient cancer xenograft in mice. [electronic resource] - Cancer biology & therapy Mar 2006 - 305-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1538-4047
10.4161/cbt.5.3.2404 doi
Animals
Antimitotic Agents--pharmacology
Cell Line, Tumor
Cell Proliferation--drug effects
Cyclin D1--metabolism
Down-Regulation
Enzyme Inhibitors--pharmacology
Female
Humans
Mice
Mice, Inbred BALB C
Neoplasm Transplantation
Nerve Sheath Neoplasms--pathology
Neurofibromatosis 1--drug therapy
Neurofibromin 1--genetics
Phytotherapy
Plant Extracts--pharmacology
Protein Serine-Threonine Kinases--antagonists & inhibitors
Signal Transduction
Transplantation, Heterologous
Zanthoxylum--chemistry
p21-Activated Kinases