The effects of supra-normal protein C levels on markers of coagulation, fibrinolysis and inflammation in a human model of endotoxemia.
Spiel, Alexander O
The effects of supra-normal protein C levels on markers of coagulation, fibrinolysis and inflammation in a human model of endotoxemia. [electronic resource] - Thrombosis and haemostasis Dec 2005 - 1148-55 p. digital
Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
0340-6245
10.1160/TH05-01-0059 doi
Adult
Blood Coagulation--drug effects
Cross-Over Studies
Double-Blind Method
Endotoxemia--blood
Endotoxins--administration & dosage
Fibrinolysin--metabolism
Fibrinolysis--drug effects
Humans
Inflammation--blood
Infusions, Intravenous
Interleukin-6--blood
Male
Monocytes--drug effects
Platelet Activation--drug effects
Protein C--administration & dosage
RNA, Messenger--metabolism
Thrombin--metabolism
Thromboplastin--genetics
Tumor Necrosis Factor-alpha--metabolism
The effects of supra-normal protein C levels on markers of coagulation, fibrinolysis and inflammation in a human model of endotoxemia. [electronic resource] - Thrombosis and haemostasis Dec 2005 - 1148-55 p. digital
Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
0340-6245
10.1160/TH05-01-0059 doi
Adult
Blood Coagulation--drug effects
Cross-Over Studies
Double-Blind Method
Endotoxemia--blood
Endotoxins--administration & dosage
Fibrinolysin--metabolism
Fibrinolysis--drug effects
Humans
Inflammation--blood
Infusions, Intravenous
Interleukin-6--blood
Male
Monocytes--drug effects
Platelet Activation--drug effects
Protein C--administration & dosage
RNA, Messenger--metabolism
Thrombin--metabolism
Thromboplastin--genetics
Tumor Necrosis Factor-alpha--metabolism