Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3.

Haacke, Annette

Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3. [electronic resource] - Human molecular genetics Feb 2006 - 555-68 p. digital

Publication Type: Journal Article

0964-6906

10.1093/hmg/ddi472 doi


Amino Acid Sequence--genetics
Animals
Ataxin-3
Cell Line
Cell Line, Tumor
Humans
Inclusion Bodies--genetics
Machado-Joseph Disease--genetics
Mice
Nerve Tissue Proteins--genetics
Neuroblastoma--genetics
Neurons--metabolism
Nuclear Proteins--genetics
Protein Processing, Post-Translational
Protein Structure, Tertiary--genetics
Repressor Proteins--genetics
Sequence Deletion--genetics
Transcription Factors