Human monocytes expressing a CEA-specific chimeric CD64 receptor specifically target CEA-expressing tumour cells in vitro and in vivo.

Biglari, A

Human monocytes expressing a CEA-specific chimeric CD64 receptor specifically target CEA-expressing tumour cells in vitro and in vivo. [electronic resource] - Gene therapy Apr 2006 - 602-10 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0969-7128

10.1038/sj.gt.3302706 doi


Animals
Carcinoembryonic Antigen--immunology
Cell Line, Tumor
Cells, Cultured
Cytokines--immunology
Genetic Engineering
Genetic Therapy--methods
Green Fluorescent Proteins--genetics
Humans
Immunotherapy--methods
Killer Cells, Natural--immunology
Mice
Mice, Nude
Monocytes--immunology
Neoplasm Transplantation
Neoplasms--immunology
Receptors, IgG--immunology
Recombinant Proteins--metabolism
T-Lymphocytes--immunology
Transplantation, Heterologous