Animal model of Gaucher's disease from targeted disruption of the mouse glucocerebrosidase gene.

Tybulewicz, V L

Animal model of Gaucher's disease from targeted disruption of the mouse glucocerebrosidase gene. [electronic resource] - Nature Jun 1992 - 407-10 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0028-0836

10.1038/357407a0 doi


Animals
Bone Marrow--metabolism
Brain--metabolism
Disease Models, Animal
Female
Gaucher Disease--genetics
Glucosylceramidase--deficiency
Homozygote
Lipid Metabolism
Liver--metabolism
Lysosomes--metabolism
Male
Mice
Mice, Transgenic
Microscopy, Electron
Mutation
Spleen--metabolism