Novel lactam NK1 antagonists with anti-emetic activity.

Hollingworth, Gregory J

Novel lactam NK1 antagonists with anti-emetic activity. [electronic resource] - Bioorganic & medicinal chemistry letters Mar 2006 - 1197-201 p. digital

Publication Type: Journal Article

0960-894X

10.1016/j.bmcl.2005.11.111 doi


Amides--chemistry
Animals
Antiemetics--chemical synthesis
Gerbillinae
Humans
Inhibitory Concentration 50
Lactams--chemical synthesis
Methylation
Molecular Structure
Receptors, Neurokinin-1--metabolism
Structure-Activity Relationship
Tachykinins--antagonists & inhibitors