Selective loss of fine tuning of Gq/11 signaling by RGS2 protein exacerbates cardiomyocyte hypertrophy.

Zhang, Wei

Selective loss of fine tuning of Gq/11 signaling by RGS2 protein exacerbates cardiomyocyte hypertrophy. [electronic resource] - The Journal of biological chemistry Mar 2006 - 5811-20 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M507871200 doi


Animals
Cells, Cultured
Disease Models, Animal
Enzyme Activation
GTP-Binding Protein alpha Subunits, Gq-G11--genetics
Humans
Hypertrophy
Isoenzymes--metabolism
Male
Mice
Mice, Transgenic
Mitogen-Activated Protein Kinases--metabolism
Myocytes, Cardiac--cytology
Phospholipase C beta
RGS Proteins--genetics
RNA, Small Interfering--genetics
Rats
Rats, Sprague-Dawley
Second Messenger Systems--physiology
Type C Phospholipases--metabolism