Quantitative determination of zebularine (NSC 309132), a DNA methyltransferase inhibitor, and three metabolites in murine plasma by high-performance liquid chromatography coupled with on-line radioactivity detection.
Beumer, Jan H
Quantitative determination of zebularine (NSC 309132), a DNA methyltransferase inhibitor, and three metabolites in murine plasma by high-performance liquid chromatography coupled with on-line radioactivity detection. [electronic resource] - Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Feb 2006 - 147-55 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Validation Study
1570-0232
10.1016/j.jchromb.2005.11.048 doi
Animals
Carbon Radioisotopes
Chromatography, High Pressure Liquid--methods
Cytidine--analogs & derivatives
DNA Modification Methylases--antagonists & inhibitors
Drug Stability
Male
Mice
Mice, Inbred Strains
Online Systems
Reproducibility of Results
Sensitivity and Specificity
Specific Pathogen-Free Organisms
Spectrophotometry, Ultraviolet
Uracil--analogs & derivatives
Uridine--blood
Quantitative determination of zebularine (NSC 309132), a DNA methyltransferase inhibitor, and three metabolites in murine plasma by high-performance liquid chromatography coupled with on-line radioactivity detection. [electronic resource] - Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Feb 2006 - 147-55 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Validation Study
1570-0232
10.1016/j.jchromb.2005.11.048 doi
Animals
Carbon Radioisotopes
Chromatography, High Pressure Liquid--methods
Cytidine--analogs & derivatives
DNA Modification Methylases--antagonists & inhibitors
Drug Stability
Male
Mice
Mice, Inbred Strains
Online Systems
Reproducibility of Results
Sensitivity and Specificity
Specific Pathogen-Free Organisms
Spectrophotometry, Ultraviolet
Uracil--analogs & derivatives
Uridine--blood