The crystal structure of TrpD, a metabolic enzyme essential for lung colonization by Mycobacterium tuberculosis, in complex with its substrate phosphoribosylpyrophosphate.
Lee, Clare E
The crystal structure of TrpD, a metabolic enzyme essential for lung colonization by Mycobacterium tuberculosis, in complex with its substrate phosphoribosylpyrophosphate. [electronic resource] - Journal of molecular biology Jan 2006 - 784-97 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-2836
10.1016/j.jmb.2005.11.016 doi
Amino Acid Sequence
Anthranilate Phosphoribosyltransferase--chemistry
Benzamidines--chemistry
Binding Sites
Catalysis
Cations, Divalent--chemistry
Conserved Sequence
Crystallography, X-Ray
Lung--microbiology
Magnesium--chemistry
Models, Molecular
Molecular Sequence Data
Mycobacterium tuberculosis--enzymology
Phosphoribosyl Pyrophosphate--chemistry
Protein Structure, Tertiary
Sequence Alignment
Sequence Homology, Amino Acid
Substrate Specificity
Tryptophan--biosynthesis
ortho-Aminobenzoates--chemistry
The crystal structure of TrpD, a metabolic enzyme essential for lung colonization by Mycobacterium tuberculosis, in complex with its substrate phosphoribosylpyrophosphate. [electronic resource] - Journal of molecular biology Jan 2006 - 784-97 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-2836
10.1016/j.jmb.2005.11.016 doi
Amino Acid Sequence
Anthranilate Phosphoribosyltransferase--chemistry
Benzamidines--chemistry
Binding Sites
Catalysis
Cations, Divalent--chemistry
Conserved Sequence
Crystallography, X-Ray
Lung--microbiology
Magnesium--chemistry
Models, Molecular
Molecular Sequence Data
Mycobacterium tuberculosis--enzymology
Phosphoribosyl Pyrophosphate--chemistry
Protein Structure, Tertiary
Sequence Alignment
Sequence Homology, Amino Acid
Substrate Specificity
Tryptophan--biosynthesis
ortho-Aminobenzoates--chemistry