Dysfunction of the cortico-basal ganglia-cortical loop in a rat model of early parkinsonism is reversed by metabotropic glutamate receptor 5 antagonism.

Oueslati, Abid

Dysfunction of the cortico-basal ganglia-cortical loop in a rat model of early parkinsonism is reversed by metabotropic glutamate receptor 5 antagonism. [electronic resource] - The European journal of neuroscience Dec 2005 - 2765-74 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0953-816X

10.1111/j.1460-9568.2005.04498.x doi


Animals
Basal Ganglia--physiopathology
Cerebral Cortex--physiopathology
Denervation
Dopamine Uptake Inhibitors
Electron Transport Complex IV--biosynthesis
Enkephalins--metabolism
Excitatory Amino Acid Antagonists--therapeutic use
In Situ Hybridization
Male
Mazindol
Neostriatum--metabolism
Nerve Net--physiology
Neurons--metabolism
Oxidopamine
Parkinson Disease, Secondary--chemically induced
Protein Precursors--metabolism
RNA, Messenger--biosynthesis
Rats
Rats, Wistar
Receptor, Metabotropic Glutamate 5
Receptors, Metabotropic Glutamate--antagonists & inhibitors
Sympatholytics
Tachykinins--metabolism
Thalamus--physiology