Amplification and disruption of the phenylacetyl-CoA ligase gene of Penicillium chrysogenum encoding an aryl-capping enzyme that supplies phenylacetic acid to the isopenicillin N-acyltransferase.

Lamas-Maceiras, Mónica

Amplification and disruption of the phenylacetyl-CoA ligase gene of Penicillium chrysogenum encoding an aryl-capping enzyme that supplies phenylacetic acid to the isopenicillin N-acyltransferase. [electronic resource] - The Biochemical journal Apr 2006 - 147-55 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1470-8728

10.1042/BJ20051599 doi


Acyltransferases--metabolism
Amino Acid Motifs
Amino Acid Sequence
Bacteriophages--genetics
Carrier Proteins--metabolism
Cloning, Molecular
Coenzyme A Ligases--chemistry
Conserved Sequence--genetics
Drug Resistance, Fungal
Gene Amplification--genetics
Gene Deletion
Genetic Complementation Test
Genomic Library
Molecular Sequence Data
Multigene Family
Penicillin-Binding Proteins--metabolism
Penicillins--biosynthesis
Penicillium chrysogenum--cytology
Peroxisomes--metabolism
Phenylacetates--metabolism
Protein Structure, Tertiary
Protein Transport
Substrate Specificity