Nfl gene inactivation in acute myeloid leukemia cells confers cytarabine resistance through MAPK and mTOR pathways.

Yin, B

Nfl gene inactivation in acute myeloid leukemia cells confers cytarabine resistance through MAPK and mTOR pathways. [electronic resource] - Leukemia Jan 2006 - 151-4 p. digital

Publication Type: Letter; Research Support, Non-U.S. Gov't

0887-6924

10.1038/sj.leu.2404033 doi


Acute Disease
Animals
Cell Death--drug effects
Cell Line, Tumor
Cytarabine--pharmacology
Drug Resistance, Neoplasm
Humans
Leukemia, Myeloid--drug therapy
Mice
Mitogen-Activated Protein Kinases--metabolism
Neurofibromin 1--deficiency
Protein Kinases--metabolism
Signal Transduction--drug effects
TOR Serine-Threonine Kinases