Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action.

Harrington, William R

Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action. [electronic resource] - Molecular endocrinology (Baltimore, Md.) Mar 2006 - 491-502 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

0888-8809

10.1210/me.2005-0186 doi


Adaptor Proteins, Signal Transducing--drug effects
Binding, Competitive
Breast Neoplasms--drug therapy
Cell Membrane--metabolism
Cell Proliferation
Cytoplasm--metabolism
Dendrimers
Dose-Response Relationship, Drug
Estradiol--metabolism
Estrogens--metabolism
Extracellular Matrix--metabolism
Extracellular Signal-Regulated MAP Kinases--drug effects
Gene Expression Regulation--drug effects
Genome--drug effects
Humans
Phosphorylation
Polyamines--chemistry
Receptors, Estrogen--metabolism
Rhodamines--chemistry
Shc Signaling Adaptor Proteins
Signal Transduction
Src Homology 2 Domain-Containing, Transforming Protein 1
Tumor Cells, Cultured
src-Family Kinases--drug effects