Impaired NADPH oxidase activity in Rac2-deficient murine neutrophils does not result from defective translocation of p47phox and p67phox and can be rescued by exogenous arachidonic acid.

Kim, Chaekyun

Impaired NADPH oxidase activity in Rac2-deficient murine neutrophils does not result from defective translocation of p47phox and p67phox and can be rescued by exogenous arachidonic acid. [electronic resource] - Journal of leukocyte biology Jan 2006 - 223-34 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0741-5400

10.1189/jlb.0705371 doi


Animals
Arachidonic Acid--immunology
Carcinogens--pharmacology
Cell Membrane--enzymology
Cells, Cultured
Enzyme Activation--drug effects
Mice
Mice, Knockout
N-Formylmethionine Leucyl-Phenylalanine--pharmacology
NADPH Oxidases--immunology
Neuropeptides--immunology
Neutrophils--cytology
Phospholipases A--immunology
Phospholipases A2
Phosphoproteins--immunology
Protein Kinase C-epsilon--immunology
Protein Transport--drug effects
Superoxides--immunology
Tetradecanoylphorbol Acetate--pharmacology
rac GTP-Binding Proteins--deficiency
rac1 GTP-Binding Protein
RAC2 GTP-Binding Protein