Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck.

Amornphimoltham, Panomwat

Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck. [electronic resource] - Cancer research Nov 2005 - 9953-61 p. digital

Publication Type: Journal Article

0008-5472

10.1158/0008-5472.CAN-05-0921 doi


Animals
Antibiotics, Antineoplastic--pharmacology
Apoptosis--drug effects
Carcinoma, Squamous Cell--drug therapy
Cell Line, Tumor
DNA, Neoplasm--biosynthesis
Female
Head and Neck Neoplasms--drug therapy
Humans
Mice
Mice, Nude
Phosphatidylinositol 3-Kinases--metabolism
Phosphorylation
Protein Kinases--metabolism
Proto-Oncogene Proteins c-akt--metabolism
Ribosomal Protein S6 Kinases, 70-kDa--metabolism
Signal Transduction--drug effects
Sirolimus--analogs & derivatives
TOR Serine-Threonine Kinases
Xenograft Model Antitumor Assays