Lack of glutathione peroxidase-1 exacerbates Abeta-mediated neurotoxicity in cortical neurons.

Crack, P J

Lack of glutathione peroxidase-1 exacerbates Abeta-mediated neurotoxicity in cortical neurons. [electronic resource] - Journal of neural transmission (Vienna, Austria : 1996) May 2006 - 645-57 p. digital

Publication Type: Comparative Study; Journal Article

0300-9564

10.1007/s00702-005-0352-y doi


Amyloid beta-Peptides--toxicity
Animals
Animals, Newborn
Blotting, Western--methods
Caspase 3
Caspases--metabolism
Cell Survival--drug effects
Cells, Cultured
Cerebral Cortex--cytology
Dose-Response Relationship, Drug
Drug Interactions
Glutathione Peroxidase--deficiency
Hydrogen Peroxide--pharmacology
Mice
Mice, Inbred C57BL
Mice, Knockout
Neurons--drug effects
Neurotoxicity Syndromes--etiology
Peptide Fragments--toxicity
Tetrazolium Salts
Thiazoles
Glutathione Peroxidase GPX1