Synthesis and biological evaluation of 3-ethylidene-1,3-dihydro-indol-2-ones as novel checkpoint 1 inhibitors.
Lin, Nan-Horng
Synthesis and biological evaluation of 3-ethylidene-1,3-dihydro-indol-2-ones as novel checkpoint 1 inhibitors. [electronic resource] - Bioorganic & medicinal chemistry letters Jan 2006 - 421-6 p. digital
Publication Type: Journal Article
0960-894X
10.1016/j.bmcl.2005.09.064 doi
Cell Proliferation--drug effects
Checkpoint Kinase 1
Crystallography, X-Ray
Drug Design
Drug Evaluation, Preclinical
Enzyme Inhibitors--chemical synthesis
HeLa Cells
Humans
Models, Molecular
Molecular Structure
Protein Kinases--drug effects
Structure-Activity Relationship
Synthesis and biological evaluation of 3-ethylidene-1,3-dihydro-indol-2-ones as novel checkpoint 1 inhibitors. [electronic resource] - Bioorganic & medicinal chemistry letters Jan 2006 - 421-6 p. digital
Publication Type: Journal Article
0960-894X
10.1016/j.bmcl.2005.09.064 doi
Cell Proliferation--drug effects
Checkpoint Kinase 1
Crystallography, X-Ray
Drug Design
Drug Evaluation, Preclinical
Enzyme Inhibitors--chemical synthesis
HeLa Cells
Humans
Models, Molecular
Molecular Structure
Protein Kinases--drug effects
Structure-Activity Relationship