Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells.

Sturrock, Anne

Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells. [electronic resource] - American journal of physiology. Lung cellular and molecular physiology Apr 2006 - L661-L673 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

1040-0605

10.1152/ajplung.00269.2005 doi


Cell Proliferation--drug effects
Cells, Cultured
Contractile Proteins--metabolism
Humans
Mitogen-Activated Protein Kinases--metabolism
Myocytes, Smooth Muscle--cytology
NADPH Oxidase 4
NADPH Oxidases--metabolism
Pulmonary Artery--cytology
Reactive Oxygen Species--metabolism
Signal Transduction--physiology
Smad Proteins--metabolism
Transforming Growth Factor beta--pharmacology
Transforming Growth Factor beta1