Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720.

Zemann, Barbara

Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720. [electronic resource] - Blood Feb 2006 - 1454-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-4971

10.1182/blood-2005-07-2628 doi


Animals
Cell Movement--drug effects
Fingolimod Hydrochloride
Flow Cytometry
Immunosuppressive Agents--pharmacology
Kinetics
Lymphocytes--drug effects
Mice
Mice, Knockout
Phosphates--metabolism
Phosphotransferases (Alcohol Group Acceptor)--deficiency
Polymerase Chain Reaction
Propylene Glycols--pharmacology
RNA, Messenger--genetics
Sphingosine--analogs & derivatives