Role of human cyclooxygenase-2 in the bioactivation of dapsone and sulfamethoxazole.

Vyas, Piyush M

Role of human cyclooxygenase-2 in the bioactivation of dapsone and sulfamethoxazole. [electronic resource] - Drug metabolism and disposition: the biological fate of chemicals Jan 2006 - 16-8 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

0090-9556

10.1124/dmd.105.006890 doi


Arachidonic Acid--metabolism
Chromatography, High Pressure Liquid--methods
Cyclooxygenase 2--metabolism
Dapsone--metabolism
Dose-Response Relationship, Drug
Edetic Acid--metabolism
Enzyme-Linked Immunosorbent Assay--methods
Hemin--metabolism
Humans
Hydrogen Peroxide--metabolism
Hydroxylamines--analysis
Protein Binding--drug effects
Sulfamethoxazole--metabolism