Treatment of mice with the suppressor of cytokine signaling-1 mimetic peptide, tyrosine kinase inhibitor peptide, prevents development of the acute form of experimental allergic encephalomyelitis and induces stable remission in the chronic relapsing/remitting form.
Mujtaba, Mustafa G
Treatment of mice with the suppressor of cytokine signaling-1 mimetic peptide, tyrosine kinase inhibitor peptide, prevents development of the acute form of experimental allergic encephalomyelitis and induces stable remission in the chronic relapsing/remitting form. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Oct 2005 - 5077-86 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
0022-1767
10.4049/jimmunol.175.8.5077 doi
Acute Disease
Animals
Carrier Proteins--physiology
Cell Line
Chronic Disease
Cytokines--biosynthesis
Disease Models, Animal
Encephalomyelitis, Autoimmune, Experimental--drug therapy
Interferon-Stimulated Gene Factor 3--antagonists & inhibitors
Interferon-gamma--administration & dosage
Mice
Mice, Inbred NZB
Molecular Mimicry--immunology
Mycobacterium tuberculosis--immunology
Peptide Fragments--administration & dosage
Peptides--administration & dosage
Protein Kinase Inhibitors--pharmacology
Protein-Tyrosine Kinases--antagonists & inhibitors
RNA, Messenger--metabolism
Recurrence
Repressor Proteins--physiology
Suppressor of Cytokine Signaling 1 Protein
Suppressor of Cytokine Signaling Proteins--physiology
Tumor Necrosis Factor-alpha--antagonists & inhibitors
Treatment of mice with the suppressor of cytokine signaling-1 mimetic peptide, tyrosine kinase inhibitor peptide, prevents development of the acute form of experimental allergic encephalomyelitis and induces stable remission in the chronic relapsing/remitting form. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Oct 2005 - 5077-86 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
0022-1767
10.4049/jimmunol.175.8.5077 doi
Acute Disease
Animals
Carrier Proteins--physiology
Cell Line
Chronic Disease
Cytokines--biosynthesis
Disease Models, Animal
Encephalomyelitis, Autoimmune, Experimental--drug therapy
Interferon-Stimulated Gene Factor 3--antagonists & inhibitors
Interferon-gamma--administration & dosage
Mice
Mice, Inbred NZB
Molecular Mimicry--immunology
Mycobacterium tuberculosis--immunology
Peptide Fragments--administration & dosage
Peptides--administration & dosage
Protein Kinase Inhibitors--pharmacology
Protein-Tyrosine Kinases--antagonists & inhibitors
RNA, Messenger--metabolism
Recurrence
Repressor Proteins--physiology
Suppressor of Cytokine Signaling 1 Protein
Suppressor of Cytokine Signaling Proteins--physiology
Tumor Necrosis Factor-alpha--antagonists & inhibitors